Book Hotels in Mission Hill, SD
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Top Mission Hill hotels

Fairfield Inn & Suites by Marriott Yankton
508 WEST 21ST STREET Yankton SD
Fully refundableReserve now, pay when you stay
$124 nightly
The price is $137 total per night from Apr 12 to Apr 13
$137 total
Apr 12 - Apr 13
Total with taxes and fees
An indoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like continental breakfast and WiFi in public areas. ...
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Reviewed on Mar 9, 2026

Comfort Inn Yankton SD
611 W 23rd Street Yankton SD
Fully refundable
$88 nightly
The price is $98 total per night from Mar 23 to Mar 24
$98 total
Mar 23 - Mar 24
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies ...
This Comfort inn was definitely comfortable and well kept. The icing on the cake was a very friendly staff!
Reviewed on Mar 14, 2026

Lewis and Clark Resort
43496 Shore Drive Yankton SD
$84 nightly
The price is $89 total per night from Mar 17 to Mar 18
$89 total
Mar 17 - Mar 18
Total with taxes and fees
A marina and a restaurant are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
great place to stay! clean rooms with great views! the water and walking path are awesome. Good staff as well!
Reviewed on Mar 16, 2026

Best Western Vermillion Inn
701 W Cherry St Vermillion SD
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $106 total per night from Mar 17 to Mar 18
$106 total
Mar 17 - Mar 18
Total with taxes and fees
This hotel features an indoor pool and a gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. There's a sauna on site, and a 24-hour ...
Friendly staff. Clean Good breakfast
Reviewed on Mar 14, 2026

Holiday Inn Express Hotel & Suites Vermillion by IHG
1200 N Dakota St Vermillion SD
$118 nightly
The price is $130 total per night from Mar 19 to Mar 20
$130 total
Mar 19 - Mar 20
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Guests will appreciate free perks like free self parking and WiFi in public areas. A 24-hour business center, ...
The hotel was being rennovated to an extreme that made it difficult. Signage is all on the floors. We were given a different room style than what we reserved (with no discount) that had outlets and blinds that did not work. No sheets or pillows were included for the pull out couch. There was renovation ...
Reviewed on Mar 1, 2026

Best Western Kelly Inn
1607 E Highway 50 Yankton SD
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $106 total per night from Mar 22 to Mar 23
$106 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Honestly we would not stay here again if we dint really have too. Our room still had a sticker on the t.v from pervious people. That tells me it did not get cleaned very well along with crumbs still on the floor. Our sliding door to the pool the handle was broken so it was hard to open and close. ...
Reviewed on Mar 9, 2026

Red Roof Inn Vermillion - U of South Dakota
1208 E Cherry St Vermillion SD
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $78 total per night from Apr 1 to Apr 2
$78 total
Apr 1 - Apr 2
Total with taxes and fees
An indoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like full breakfast and WiFi in public areas. A snack ...
Bathroom needs to be updated. Have stayed in several rooms now and all need plumbing attention in the showers.
Reviewed on Feb 23, 2026

Econo Lodge Inn & Suites Yankton
2410 Broadway Ave Yankton SD
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $76 total per night from Mar 22 to Mar 23
$76 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Got to the peoperty doors are boarded up. This place should be removed from hotels.
Reviewed on Mar 15, 2026

Holiday Inn Express & Suites Yankton by IHG
2607 Broadway Ave Yankton SD
Fully refundable
$110 nightly
The price is $121 total per night from Apr 16 to Apr 17
$121 total
Apr 16 - Apr 17
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Mission Hill hotel reviews by fellow wanderers

Lewis and Clark Resort
5 out of 5
Posted 7 hours ago
Travelocity Verified Review
"great place to stay! clean rooms with great views! the water and walking path are awesome. Good staff as well!"
A verified traveler stayed at Lewis and Clark Resort






